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Summary
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DB built by FlyBase

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Gene: IRSp53 FBgn0052082

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Description

Insulin receptor substrate 53 kDa

Gene Synonyms

Location

Primary_assembly 3L: 11,136,049-11,163,984 forward strand.

BDGP6.46:AE014296.5

About this gene

This gene has 4 transcripts (splice variants) and 54 orthologues.

Transcripts

Show transcript tableHide transcript table

Name	Transcript ID	bp	Protein	Translation ID	Biotype	UniProt	RefSeq	Flags
IRSp53-RA	FBtr0076216	5246	1076aa	FBpp0075945	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A2RVI1 Q8IQE6	-	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
IRSp53-RB	FBtr0113422	3334	630aa	FBpp0112334	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A8JNR3 Q6NNT5	-	APPRIS P4: Where the APPRIS core modules are unable to choose a clear principal CDS and there is more than one variant with a distinct (but consecutive) CCDS identifiers, APPRIS selects the longest CCDS isoform as the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P4,
IRSp53-RD	FBtr0334096	3265	629aa	FBpp0306220	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A8JNR2	-	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
IRSp53-RE	FBtr0344833	3163	646aa	FBpp0311148	Gene/transcipt that contains an open reading frame (ORF).Protein coding	X2JCT5	-	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,

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Summary

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