Necator americanus (New World hookworm, N. amaericanus Hunan isolate) (N_americanus_v1)

NOTE: The genome sequence and annotation for this nematode are updated in Ensembl Metazoa infrequently. For the latest genome and annotation, please visit WormBase ParaSite.

About Necator americanus

The hookworm Necator americanus is a parasitic nematode commonly known as the New World hookworm. Hookworms infect around 700 million people globally, causing a disease burden of 1.5-22.1 million disability-adjusted life years. Around 85% of all hookworm infections in humans are coming from this species causing Necatoriasis, a disease characterised by impairment of development in children, anaemia and malnutrition in pregnant women.

Unembryonated Necator americanus eggs are passed in the stool and under favourable conditions the larvae hatch in soil. After maturating in the soil, the larvae becomes infective and in contact with the human host, typically bare feet, penetrate the skin and enter the bloodstream. After being carried to the lungs, they make it up to the bronchial tree and are swallowed. Larvae then reach the jejunum of the small intestine, where they mature into adults.

Picture credit: Jasper Lawrence Creative Commons Attribution 4.0 via Wikimedia Commons (Image source)

Taxonomy ID 51031

Data source McDonnell Genome Institute

More information and statistics

Genome assembly: N_americanus_v1

More information and statistics

Download DNA sequence (FASTA)

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Gene annotation

What can I find? Protein-coding and non-coding genes, splice variants, cDNA and protein sequences, non-coding RNAs.

More about this genebuild

Download genes, cDNAs, ncRNA, proteins - FASTA - GFF3

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Comparative genomics

What can I find? Homologues, gene trees, and whole genome alignments across multiple species.

More about comparative analyses

Phylogenetic overview of gene families

Download alignments (EMF)


This species currently has no variation database. However you can process your own variants using the Variant Effect Predictor:

Variant Effect Predictor