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NOTE: The genome sequence and annotation for B. malayi are updated in Ensembl Metazoa infrequently. The data here correspond with WormBase WS279. For the latest genome and annotation, please visit WormBase ParaSite or WormBase.
About Brugia malayi
Brugia malayi is a gonochoristic, parasitic nematode. It is one of the causative agents of lymphatic filariasis in humans. Lymphatic filariasis, is a chronic, debilitating condition characterized by swelling of the lower limbs. The lifecycle of B. malayi involves four life stages in a mosquito host (Culex, Aedes and Anopheles), after which infectious microfilariae are transmitted to human hosts. Due to this it is restricted to South and South East Asia. B. malayi contains an Wolbachia endosymbiont, with horizontal gene transfer occurring. It is one of the tropical diseases targeted for elimination by the year 2020 by the World Health Organization.
- B. malayi data at WormBase.
- B. malayi data at WormBase ParaSite.
- Filariasis Research Reagents Center.
- Brugia malayi TRS strain Wolbachia Genome at Ensembl Genomes.
- Lymphatic Filariasis, World Health Organization.
Picture credit: Public domain via Wikimedia Commons (Image source)
Taxonomy ID 6279
Data source WormBase
Comparative genomics
What can I find? Homologues, gene trees, and whole genome alignments across multiple species.
More about comparative analyses
Phylogenetic overview of gene families
Download alignments (EMF)
Variation
This species currently has no variation database. However you can process your own variants using the Variant Effect Predictor: