A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical,
APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant.
APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene.
APPRIS ALT1: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that is conserved in at least three tested species.
APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene.
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Low complexity (Seg)
Low complexity peptide sequences identified by Seg.
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AFDB-ENSP mappings
Protein features that represent the mapping between Ensembl proteins (ENSP) and AlphaFoldDB protein structures (including their corresponding chains). Imported via UniProt mappings
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Superfamily
Protein domains and motifs from the SUPERFAMILY database.
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SMART
Protein domains and motifs from the SMART database.
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Pfam
Protein domains and motifs from the Pfam database.
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