Ixodes scapularis (ISE6) (IscaI1)

The Ixodes scapularis data and its display on Ensembl Genomes are made possible through a joint effort by the Ensembl Genomes group and VectorBase, a component of VEuPathDB.

Picture credit (public domain): Scott Bauer (USDA) 1998

About Ixodes scapularis

Ixodes scapularis, the black-legged tick, is a hard-bodied tick from the Ixodidae family. I. scapularis is the primary vector for Lyme disease, transmitting the pathogenic bacterium Borrelia burgdorfei.

ISE6 cell line

The ISE6 cell line (Ixodes scapularis embryonic 6) is an extensively used tick cell line that has been successfully used to culture many tick-associated bacteria (Rickettsia, Anaplasma, Ehrlichia, and Neoehrlichia), to study vector-pathogen interactions and differential expression of pathogen genes during growth in mammalian and arthropod cells, to carry out growth and propagation of Arboviruses, and are an important model for molecular study using RNAi of tick genes important for decreasing pathogen transmission and understanding tick biology ( "An Ixodes scapularis cell line with a predominantly neuron-like phenotype", Oliver et al, Exp Appl Acarol. 2015 Jul; 66(3): 427–442. doi: 10.1007/s10493-015-9908-1).

Source: VectorBase

Picture credit (public domain): Scott Bauer (USDA) 1998

Taxonomy ID 6945

Data source J. Craig Venter Institute

More information and statistics

Genome assembly: IscaI1

More information and statistics

Download DNA sequence (FASTA)

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Gene annotation

What can I find? Protein-coding and non-coding genes, splice variants, cDNA and protein sequences, non-coding RNAs.

More about this genebuild

Download genes, cDNAs, ncRNA, proteins - FASTA - GFF3

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Comparative genomics

What can I find? Homologues, gene trees, and whole genome alignments across multiple species.

More about comparative analyses

Phylogenetic overview of gene families

Download alignments (EMF)

Variation

This species currently has no variation database. However you can process your own variants using the Variant Effect Predictor:

Variant Effect Predictor

About this species