About Anopheles gambiae
Anopheles gambiae senso stricto is the primary mosquito vector responsible for the transmission of malaria in most of sub-Saharan Africa. It is a member of a species complex that includes at least seven morphologically indistinguishable species in the Series Pyretophorus in the Anopheles subgenus Cellia. An. gambiae feeds preferentially on humans and is one of the most efficient malaria vectors known. Anopheles gambiae senso stricto is now known to consist of two genetically distinct forms or incipient species, known formally as the An. gambiae M and An. gambiae S forms.
Picture credit (public domain): James Gathany (CDC) 1994
What can I find? Homologues, gene trees, and whole genome alignments across multiple species.
Download alignments (EMF)
|Anopheles gambiae : Drosophila melanogaster||TRANSLATED_BLAT|
|Anopheles gambiae : Anopheles darlingi||TRANSLATED_BLAT|
|Anopheles gambiae : Culex quinquefasciatus||TRANSLATED_BLAT_NET|
|Anopheles gambiae : Aedes aegypti||TRANSLATED_BLAT|
|Anopheles gambiae : Ixodes scapularis||TRANSLATED_BLAT_NET|
|Anopheles gambiae : Drosophila melanogaster||TRANSLATED_BLAT_NET|
|Anopheles gambiae : Culex quinquefasciatus||TRANSLATED_BLAT|
|Anopheles gambiae : Pediculus humanus||TRANSLATED_BLAT_NET|
|Anopheles gambiae : Aedes aegypti||TRANSLATED_BLAT_NET|
|Anopheles gambiae : Anopheles darlingi||TRANSLATED_BLAT_NET|
What can I find? Microarray annotations.
EST and Protein Alignments
WU-BlastX was used to map UniProtKB proteins onto the Anopheles gambiae genome. The datasets used were: Aedes, mosquito, drosophilid, arthropod, metazoan, eukaryotic, and non-eukaryotic proteins. The wider taxonomic groups exclude any of the more specific groups, e.g. the arthropod dataset excludes mosquito and drosophilid proteins. (Example: 2L:39300000-39320000).
GeneWise was used to map proteins from non-redundant taxonomic levels onto the Anopheles gambiae genome. The protein datasets used were: Anopheles (UniProtKB and community annotation), Aedes (VectorBase), drosophilid (FlyBase), and all UniProtKB (Example: 2L:39308000-39320000).
Approximately 8500 community annotations are mapped to the genome (Example: 2L:155000-225000).