Anopheles sinensis (China) Assembly and Gene Annotation
About Anopheles sinensis
Anopheles sinensis is considered an important vector of P.vivax in China and Korea. It is common throughout South East Asia from Pakistan to Japan and as far south as Thailand and Indonesia.
The immature stages of An. sinensis are primarily found in lowland, shallow, fresh-water habitats with emergent and/or floating vegetation in open agriculture lands (mainly rice fields). They also utilise stream margins, irrigation ditches, ponds, marshes, swamps, bogs, pits, stump ground holes, grassy pools, flood pools, stream pools, rock pools, seepage-springs and wheel tracks. Shading requirements vary, but this species is more often associated with exposed and sunlit aquatic environments.
Resting and feeding preferences
Female An. sinensis feed throughout the night, with peak activity apparently occurring at different hours depending on locality. Under normal circumstances, females are predominantly zoophilic and exophilic, infrequently biting humans in the presence of their preferred hosts (buffalo and cattle), and are rarely found inside human habitations. In northern temperate climates, An. sinensis females hibernate in sheltered places from the end of October.
There is evidence that An. sinensis is refractory to Plasmodium falciparum, but it is still considered an important vector of P. vivax malaria in both China and Korea. It is the most common anopheline species in Japan, where it is regarded as an important historical vector of malaria. An. sinensis is considered to be a minor malaria vector in Indonesia (Sumatra only) and has little or no involvement in malaria transmission in Thailand due to its zoophilic and exophilic behaviour and its prevalence primarily in areas where there is little or no malaria. Along the border between North and South Korea, it has been reported that An. sinensis comprised 80% of the anopheline mosquitoes attacking humans during an outbreak of P. vivax malaria but studies suggest that An. sinensis is a less effective vector of malaria in Korea than An. lesteri. The zoophilic and exophilic behaviour of this species suggests its vectorial capacity may be high only in the presence of large population densities.
This text was modified from Sinka ME et al. (2011) The dominant Anopheles vectors of human malaria in Asia-Pacific: occurrence data, distribution maps and bionomic précis Parasites & Vectors 4:89.
The China strain is an inbred laboratory strain that was sequenced as
described in the publication
"Genome sequence of Anopheles sinensis provides insight into genetics basis of mosquito competence for malaria parasites.
", Zhou et al, 2014. (PMID:24438588).
Assembled and submitted by Nanjing Medical University.
AsinC2.2 gene set
Community annotation patch build for July 2019
- Genome sequence of Anopheles sinensis provides insight into
genetics basis of mosquito competence for malaria
Zhou D, Zhang D, Ding G, Shi L, Hou Q, Ye Y, Xu Y, Zhou H, Xiong C, Li S et al. 2014. BMC Genomics. 15
- The dominant Anopheles vectors of human malaria in the Asia-Pacific
region: occurrence data, distribution maps and bionomic
Sinka ME, Bangs MJ, Manguin S, Chareonviriyaphap T, Patil AP, Temperley WH, Gething PW, Elyazar IR, Kabaria CW, Harbach RE et al. 2011. Parasit Vectors. 4
Picture credit: VectorBase.org
|Assembly||AsinC2, INSDC Assembly GCA_000441895.2, Jul 2014|
|Golden Path Length||220,777,669|
|Genebuild method||Import build|
|Non coding genes||342|
|Small non coding genes||340|
|Long non coding genes||2|