NOTE: The genome sequence and annotation for this nematode are updated in Ensembl Metazoa infrequently. For the latest genome and annotation, please visit WormBase ParaSite.
About Necator americanus
The hookworm Necator americanus is a parasitic nematode commonly known as the New World hookworm. Hookworms infect around 700 million people globally, causing a disease burden of 1.5-22.1 million disability-adjusted life years. Around 85% of all hookworm infections in humans are coming from this species causing Necatoriasis, a disease characterised by impairment of development in children, anaemia and malnutrition in pregnant women.
Unembryonated Necator americanus eggs are passed in the stool and under favourable conditions the larvae hatch in soil. After maturating in the soil, the larvae becomes infective and in contact with the human host, typically bare feet, penetrate the skin and enter the bloodstream. After being carried to the lungs, they make it up to the bronchial tree and are swallowed. Larvae then reach the jejunum of the small intestine, where they mature into adults.
Taxonomy ID 51031
Data source McDonnell Genome Institute
What can I find? Protein-coding and non-coding genes, splice variants, cDNA and protein sequences, non-coding RNAs.
Download genes, cDNAs, ncRNA, proteins - FASTA - GFF3
What can I find? Homologues, gene trees, and whole genome alignments across multiple species.
More about comparative analyses
Phylogenetic overview of gene families
Download alignments (EMF)
This species currently has no variation database. However you can process your own variants using the Variant Effect Predictor: