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DB built by FlyBase

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Gene: HUWE1 FBgn0030674

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Description

HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1

Gene Synonyms

Location

Primary_assembly X: 15,712,628-15,731,935 forward strand.

BDGP6.32:AE014298.5

About this gene

This gene has 7 transcripts (splice variants), 124 orthologues and 12 paralogues.

Transcripts

Show transcript tableHide transcript table

Name	Transcript ID	bp	Protein	Translation ID	Biotype	UniProt	RefSeq	Flags
HUWE1-RH	FBtr0340304	16609	5151aa	FBpp0309265	Gene/transcipt that contains an open reading frame (ORF).Protein coding	X2JF73	NM_001298359 NM_001298359.1 NP_001285288 NP_001285288.1	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P5: Where the APPRIS core modules are unable to choose a clear principal variant and none of the candidate variants are annotated by CCDS, APPRIS selects the longest of the candidate isoforms as the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P5,
HUWE1-RD	FBtr0339687	16606	5150aa	FBpp0308744	Gene/transcipt that contains an open reading frame (ORF).Protein coding	X2JC16	NM_001298361 NM_001298361.1 NP_001285290 NP_001285290.1	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
HUWE1-RF	FBtr0339689	16537	5127aa	FBpp0308746	Gene/transcipt that contains an open reading frame (ORF).Protein coding	Q8T3L0 X2JKH9	NM_001298363 NM_001298363.1 NP_001285292 NP_001285292.1	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
HUWE1-RE	FBtr0339688	16504	5116aa	FBpp0308745	Gene/transcipt that contains an open reading frame (ORF).Protein coding	X2JDY2	NM_001298362 NM_001298362.1 NP_001285291 NP_001285291.1	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
HUWE1-RC	FBtr0339686	16168	5145aa	FBpp0308743	Gene/transcipt that contains an open reading frame (ORF).Protein coding	X2JFK0	NM_001298360 NM_001298360.1 NP_001285289 NP_001285289.1	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
HUWE1-RB	FBtr0074082	16147	5146aa	FBpp0073898	Gene/transcipt that contains an open reading frame (ORF).Protein coding	Q9VXR3	NM_132831 NM_132831.2 NP_573059 NP_573059.1	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
HUWE1-RG	FBtr0339690	16012	5101aa	FBpp0308747	Gene/transcipt that contains an open reading frame (ORF).Protein coding	X2JF83	NM_001298364 NM_001298364.1 NP_001285293 NP_001285293.1	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,

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Summary

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Gene-based displays